MyBioSource.com's TNFSF12 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, and Western Blot. The TNFSF12 Antibody was generated using TNFSF12, and TNFSF12-TNFSF13 as the antigen and it reacts with Human, and Mouse.
Description
Description: TNFSF12 Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Belongs to the tumor necrosis factor family. Homotrimer (Potential). Interacts with the angiogenic factor AGGF1/VG5Q.
Subunit Structure: Homotrimer (Probable). Interacts with the angiogenic factor AGGF1/VG5Q.
Post-translational Modifications: The soluble form derives from the membrane form by proteolytic processing.
Similarity: Belongs to the tumor necrosis factor family